Imaging & Inspection


Zeiss Axiotech 100 HD Microscope

Carl Zeiss Axiotech 100 HD Microscope

The Zeiss Axiotech microscope features 5x, 10x, 20x, 50x and 100x objectives with both bright-field and dark-field illumination. Additionally, the microscope is outfitted with a MicroImage 1093 camera system (A209 Camera; CCU109 Controller), which is connected to a display monitor and Imaging Source DFG/SV1 capture card for color still and video recording.


Cascade Microtech RHM-06 Probe Station with Olympus SZ60 Microscope

Cascade Microtech RHM-06 Probe Station with Olympus SZ60 Microscope

The Cascade probe station has a 150 mm stage with x/y/z movement. Three Alessi 3-axis (100 TPI) probe micropositioners are provided.

The Olympus zoom microscope is equipped with 20x eyepieces for magnification to 126x (1x to 6.3x), with a working distance of 100 mm. An optional conversion lens offers additional 1.5x magnification and a 56 mm working distance. A Techniquip FOI-150 fiber optic ring illuminator is attached.


Motic BA310MET-T Microscope

Motic BA310MET-T Microscope

The Motic metallurgical microscope is fitted with 5x, 10x, 20x, 50x and 100x objectives. An HBO 50 arc lamp provides bright field illumination.


Unitron Z10 Stereo Zoom Microscope

Unitron Z10 Stereo Zoom Microscope

The Unitron zoom microscope is equipped with 10x eyepieces for magnification to 80x, with a working distance of 78 mm. A Dolan Jenner LED dual goose-neck light source provides raking light illumination; a Unitron 230 LED ring light is also available.


Leica StereoZoom 4 Microscope

Leica StereoZoom 4 Microscope

The Leica zoom microscope is equipped with 20x eyepieces for magnification to 60x, with a working distance of 107 mm. An American Optical light source provides raking light illumination; a Unitron 230 LED ring light is also available.


CMADP Upcoming Events

Special seminar by Dr. James P. Landers
Commonwealth Professor in Chemistry,
Mechanical Engineering & Pathology
University of Virginia

Wednesday, May 17, 2017 at 3:00pm
Simons Auditorium, HBC, West Campus

"Integrated Microfluidic Systems for Forensic DNA Analysis"
In 2006, we demonstrated that microfluidic technology could provide a ‘lab-on-a-chip’ solution for real-world genetic analysis. Sample-in/answer-out functionality was shown for the detection of bacteria in mouse blood and in a human nasal swab, with a sub-30 minute analytical time for DNA extraction, amplification, electrophoretic separation and detection. We extrapolated these technology developments to the analysis of short tandem repeats (STR) in human DNA; these clinically-insignificant (presumably) tetranucleotide sequences function effectively for statistically-relevant matching in human identification. Our efforts led to the development of a commercializable system designed for implementation in crime labs for STR profiling convicted felons or, in some states, profiling arrestees in booking stations. An intricate but functional microfluidic architecture allowed sample-to-profile to be achieved from a cheek swab in less than 80 minutes, using nanoliter flow control, infrared thermocycling and rapid electrophoretic separation of DNA with 5-color fluorescence detection. We have since demonstrated the fabrication of hybrid microdevices composed of inexpensive polymeric materials, many of these commercial-off-the-shelf. We have designed, built and functionalized fully-integrated DNA analysis chemistry/microfluidics on a rotationally-driven system the size of a compact disc. With this system, DNA can be extracted from a swab, PCR amplified to generate an abundance of DNA fragments of the STR loci, followed by resolution of those fragments in a separation in a 4 cm Leff channel that is complete in <300 sec with a 2-base resolution. The processes that allow for swab in–profile out microfluidics are carried out on an instrument that can be carried in one hand and weighs ~14 lbs, ultimately allowing for facile rapid human identification/screening in the field.
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